This chapter explores the transformative role of Artificial Intelligence (AI) in reshaping knowledge work and professional services. As AI technologies evolve, they are poised to enhance productivity, streamline workflows, and introduce new methods of decision-making. The chapter examines the opportunities AI presents, particularly in automating routine tasks, augmenting professional roles, and personalizing services. However, challenges such as data quality, resistance to change, and ethical considerations remain significant barriers to successful AI adoption. The impact of AI on job design and professional roles is also explored, highlighting the potential for hybrid roles that combine human expertise with AI capabilities. Finally, strategies for organizations to prepare for an AI-driven future are discussed, including upskilling, ethical frameworks, and the importance of collaboration. By understanding and addressing these factors, organizations can thrive in an AI-driven landscape, unlocking new possibilities for knowledge work and professional services.