The Sustainable Development Goals (SDGs) see AI at their core, as it drives innovation across various sectors. Using the data from social, environmental, and economic domains, AI interventions can generate cross-cutting waves to drive the achievement of many of the SDGs together. This chapter focuses on the specifics of good health promotion as well as disease detection and prevention using artificial intelligence, with an emphasis on breast and cervical cancer. It also explores the role of AI in Africa in the development of proper institutions that are essential for peace, justice, and the rule of law. The chapter describes several topics, including the incorporation of AI with blockchain to improve voting systems and other essential fields.