This review article provides a detailed summary of current advances in the field of heterogeneous catalysis using silver nanoparticles. The applications of Ag nanoparticles have received a lot of attention over the past few years. The simple synthetic protocols and their green chemistry approach have raised the popularity of novel nanocatalysts. Moreover, the efforts of various researchers to make suitable support for catalysts (carbon azides, mesoporous Ag/mCTFs, reduced graphene oxides, NHC polymers, carbon nanofibers, knitting aryl network polymers, etc.) have introduced the flexibility of the nanoparticles. Their applications have been reported in a varied number of reactions, being reduction, epoxidation, cyclization of alkynes, N-alkylation, CO2 incorporation, photochemical reactions, Diels–Alder cycloaddition, and Suzuki–Miyaura cross-coupling used in production of several physiologically and therapeutically significant compounds. This review provides the relevant information from the research through the past few years, required for the advancements and further research on the catalytic ability of silver nanoparticles.