This chapter explores the role of Artificial Intelligence (AI) in optimizing business models through iterative planning. As AI continues to advance, it offers entrepreneurs powerful tools for data-driven decision-making, enhancing customer insights, market segmentation, dynamic pricing, and resource allocation. The chapter examines key AI technologies such as machine learning, natural language processing, and AI-powered simulations, which enable continuous refinement and adaptation of business strategies. It also addresses challenges such as data privacy, AI transparency, potential biases, and the balance between automation and human intuition. Ethical considerations, including the responsible use of AI, are discussed to ensure sustainable innovation. The chapter concludes by exploring future trends, including autonomous decision-making and the democratization of AI, emphasizing its potential to transform business models and drive long-term success.