As the field of social entrepreneurship expands, so will demand for education, support services, and finance to facilitate these activities. Rigorous tools for evaluating social ventures’ potential, and founders’ capabilities, will be required. The Social Entrepreneur Quotient (SEQ) is a psychometric scale encompassing six dimensions: creativity, ethics, openness to change, risk-taking, autonomy, and achievement motivation. Through SEQ testing of an international sample of participants in a massive open online course on social enterprise, this paper places in conversation the significance of individual social entrepreneur traits and the contextually embedded nature of social enterprise in the Global North and South.