As of 2011, Thailand reached Upper Middle Income Status with Gross National Income (GNI) almost doubling and considerable reductions in poverty levels over the previous decade. Thailand has a track-record of enthusiastically encouraging the socio-economic development of its neighboring “CLMV” countries (Cambodia, Laos, Myanmar, Vietnam). In order to administer this support, in 2004, a Royal Decree was promulgated to establish the Thailand International Development Cooperation Agency (TICA) under the Ministry of Foreign Affairs. In 2005 the Neighboring Countries Economic Development Cooperation Agency (NEDA) was also established as an independent public body, responsible for financing investment projects in neighboring countries. This paper undertakes a review of Thai experience on development cooperation paying particular attention to the evolving institutional framework for such cooperation.