The rapid advancement of artificial intelligence (AI) is reshaping entrepreneurial practice, prompting a reconsideration of the psychological constructs underpinning entrepreneurial mindsets. Traditionally anchored in traits such as creativity, resilience, risk tolerance, and self-efficacy, entrepreneurial psychology now faces new challenges and opportunities in an AI-mediated environment. This chapter explores the historical evolution of mindset research, identifies core psychological dimensions, and examines how AI reconfigures cognition, identity, and decision-making. It highlights both the benefits of AI, such as augmented cognition and techno-creativity, and the dilemmas entrepreneurs face, including overreliance on algorithms, ethical tensions, and digital burnout. The chapter further outlines emerging constructs—such as algorithmic trust and hybrid human–machine creativity—and calls for adaptive educational and policy frameworks. Ultimately, it argues for a synergistic model where entrepreneurial psychology and AI co-evolve to enhance innovation, responsibility, and resilience