The US-Israel axis started an unprovoked war and aggression against Iran. Iran's supreme leader, Ayatollah Ali Khamenei and Defence Minister, Army Chief have been killed, as have been scores of civilians, including over 150 schoolgirls. The US - Israel combined operation using high-precision weapons costing millions of dollars and kamikaze drones continues to target the Iranian leadership with the objective of regime change. Iran has retaliated by bombing US bases and Israel in the fragile oil-rich Gulf region. This war of attrition escalates, lives are lost, destruction and wanton devastation underscore strategic objectives of the empire and its desire for global hegemony. Globally, countries are appealing for cease fire and de-escalation.