The study contributes to startup ecosystem advancement by delving into the performance complexity of the new endeavors, holistically examining all possible quantitative and qualitative parameters and their intricacies affecting system functioning efficacy, venture resilience, and long-term sustainability. Employing a Modified Total Interpretive Structural Modeling (M-TISM) framework, the study identifies a four-tier hierarchical structure of core value drivers, with the institutional environment to be the foundation strengthening the entire system, with mentor support as the key pillar and founders to be the key actors driving the output of the successful ecosystem-the ventures, ideas, and financial system. The interpretive linkages, derived from an extensive literature base, are cross-verified through expert-based focus group discussions to ensure conceptual robustness. The findings underscore the need for supportive policy frameworks, inclusive institutional reform, and regionally balanced incubator networks to foster equitable and durable startup ecosystems. This study provides actionable insights for policymakers, emerging entrepreneurs, and ecosystem stakeholders aiming to develop resilient entrepreneurial infrastructures that foster innovation, mitigate systemic vulnerabilities, and support inclusive economic development.