This chapter provides a comprehensive analysis of the evolving role of artificial intelligence (AI) and the concurrent ethical transformations from the present day to 2050. The chapter examines the trajectory of AI development, its societal implications, and the dynamic ethical landscape that shapes and is shaped by these technological advancements. The chapter begins by establishing the current state of AI, highlighting its applications across various sectors including healthcare, finance, education, and environmental management. We discuss the present capabilities of artificial intelligence technology, while also addressing current ethical concerns such as algorithmic bias, privacy infringements, and the digital divide. We have taken the liberty of projecting the art and science of possibilities, so the projections need to be seen in that light. It is difficult to project pace and adoption of technology with any certainty, but the chapter tries to draw from learned futurists with contrasting viewpoints as the basis to draw our own conclusions. Some may consider the projects as absurd fantasy. Over eons, humanity has progressed from thinking to doing the impossible. Throughout the chapter, the needed co-evolution of AI capabilities and ethical thinking is emphasized. The authors trace the development of AI ethics from its current focus on fairness and transparency to more complex considerations of machine consciousness and the rights of artificial entities. We have explored AI and ethical evolution in the areas of healthcare, transportation, and manufacturing industry to illustrate our points. The chapter closes by reflecting on the transformative potential of AI to reshape not just our technological landscape, but our fundamental understanding of ethics, humanity, and our place in the universe. © 2026 selection and editorial matter, Naresh Singh and Ram B. Ramachandran; individual chapters, the contributors.