This chapter focuses on positive adolescent development and the role of gratitude in particular in promoting adolescent well-being. A global view on the subject is offered, with a specific focus on the Indian cultural context. The chapter consists of three main sections. The first section offers various perspectives on adolescent development, emphasizing a strengths-based approach. It highlights empirical findings on how gratitude benefits adolescents. This section also presents the cross-cultural and indigenous Indian aspects of gratitude. The second part describes an empirical study involving gratitude journaling among Indian adolescents. Study findings and implications are discussed. The third and final section of this chapter presents both Indian and international scenarios towards positive adolescent development and concludes by proposing future recommendations.