This chapter proposes nondualism as a foundation for the methodological reconstruction of IR. It uses Global IR as an entry point to address the persistence of binary thinking that structures both mainstream and critical approaches within the discipline. While Global IR seeks to overcome such binaries, it nonetheless remains partly constrained by dualist assumptions at the level of methodology. Reframing Global IR through three generations—non-Western, postcolonial/decolonial, and nondualist—the discussion shows how the first two, organised around strategies of inclusion and juxtaposition, continue to reproduce dualist geo-epistemic divisions, while the third, nondualist IR, advances a mode of reconciliation that moves beyond binary divisions and carries discipline-wide methodological implications. Nondualism is conceptualised as “deep relationalism” and advanced as the basis of a research programme. The chapter concludes by outlining the book’s methodological architecture, in which each contribution develops a nondualist methodological model through a shared analytical sequence, collectively advancing a post-binary framework for analysing global political life.