This section studies the strategic dimensions that Culture of Organizational plays for sustainable business practices through in the Horn of Africa which faces rapid economic development alongside special difficulties. The study analyzes data from 385 participants using KMO to check sample adequacy as well as CFA for measurement model validation as well as SEM based on AMOS software for variable relationship analysis. The study demonstrates that organizations through strong cultures lead the adoption of sustainable practices since they benefit from common values as well as shared organizational norms that drive environmental responsibility together through social equity standards. Organizations practicing adaptive cultures demonstrate better success rates in sustainability initiative implementation which strengthens their market position as well as organizational stability when encountering regional challenges. The study explores how these outcomes affect decision-making authorities as well as business executives who should establish sustainability as their fundamental strategy.